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Detection of Rare Mutations in CtDNA Using Next Generation Sequencing
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Enhanced structural variant and breakpoint detection using SVMerge by integration of multiple detection methods and

Kim Wong1, Thomas M Keane, James Stalker

  • 1Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK. kw10@sanger.ac.uk

Genome Biology
|January 4, 2011
PubMed
Summary

SVMerge integrates structural variant (SV) calls for improved detection and breakpoint refinement. This pipeline enhances accuracy and reduces false discoveries in genomic analyses.

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