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Modelling the way Ku binds DNA

Shaowen Hu1, Francis A Cucinotta

  • 1Universities Space Research Association, Division of Space Life Sciences, Houston, TX 77058, USA. shaowen.hu-1@nasa.gov

Radiation Protection Dosimetry
|January 4, 2011
PubMed
Summary

Researchers modeled the full-length Ku heterodimer to understand its role in DNA repair. Simulations revealed key structural and dynamic features of Ku in both free and DNA-bound states, aiding non-homologous end joining research.

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