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Fractures: Bone Repair

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
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Updated: Jun 5, 2026

Use of Human Perivascular Stem Cells for Bone Regeneration

Use of Human Perivascular Stem Cells for Bone Regeneration

Published on: May 25, 2012

Bone regeneration using particulate grafts: an update.

Amparo Aloy-Prósper¹, Laura Maestre-Ferrin, David Peñarrocha-Oltra

¹Faculty of Medicine and Dentistry, Universityof Valencia, Valencia, Spain. maria.penarrocha@uv.es

Medicina Oral, Patologia Oral Y Cirugia Bucal

|January 4, 2011

Summary

Particulate bone grafts effectively repair localized alveolar defects, showing high dental implant success rates between 85.7% and 100%. Complications are minimal, making them a viable option for bone regeneration.

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Area of Science:

Dental implantology
Bone regeneration
Periodontology

Background:

Particulate bone grafts are utilized for bone regeneration in dental implantology.
Evaluating the success of dental implants placed in grafted areas is crucial for treatment planning.

Purpose of the Study:

To review publications on bone regeneration using particulate grafts.
To evaluate the success of dental implants placed in regenerated bone areas.

Main Methods:

A Medline search was conducted for articles published between 1999 and 2009.
Included studies involved at least two patients receiving particulate grafts (autologous, homologous, xenogenic, or substitutes) for dental implant placement.
Excluded studies involving block grafting; 11 studies were evaluated.

Main Results:

Particulate grafts are indicated for small bone defects like dehiscences and fenestrations, often with barrier membranes.
Graft healing typically required 6-9 months before implant placement.
Implant survival rates ranged from 90.9% to 100%, with success rates from 85.7% to 100%.

Conclusions:

Particulate grafts are effective for correcting localized alveolar process defects.
Complications associated with particulate grafting are infrequent.
Dental implants placed in these reconstructed areas demonstrate high success rates (85.7%-100%).