Cyanoacrylate versus Collagen Membrane as a Sealing for Alveolar Ridge Preservation: A Randomized Clinical Trial

Area of Science:

• Dentistry
• Oral Surgery
• Regenerative Medicine

Background:

• Alveolar ridge preservation is crucial for successful immediate dental implant placement.
• Comparing different sealing materials for xenograft-based alveolar ridge preservation is essential.
• Evaluating long-term bone stability and soft tissue healing is critical.

Purpose of the Study:

• To compare the efficacy of cyanoacrylate versus collagen membrane for sealing in alveolar ridge preservation.
• To assess clinical and radiological outcomes of immediate dental implants placed after extraction with different sealing methods.
• To evaluate changes in alveolar bone width, clinical attachment level, and marginal bone loss.

Main Methods:

• Randomized clinical trial with 140 patients undergoing alveolar ridge preservation with xenografts.
• Comparison of cyanoacrylate (CMX group) versus collagen membrane (CX group) for sealing.
• Immediate dental implant placement post-extraction, with evaluations at 3, 12, and 18 months.

Main Results:

• The cyanoacrylate group (CMX) showed a significantly greater reduction in buccolingual bone width at 3 months (p < 0.005).
• Clinical attachment level (CAL) and marginal bone loss (MBL) were significantly higher in the CMX group (p < 0.005 and p < 0.001, respectively).
• Five instances of membrane exposure occurred in the CMX group.

Conclusions:

• Cyanoacrylate appears to provide superior clinical and radiological results for alveolar ridge preservation compared to collagen membranes.
• The findings suggest potential benefits of cyanoacrylate in maintaining bone dimensions and reducing marginal bone loss.
• Further research may explore optimizing cyanoacrylate application to mitigate complications like membrane exposure.