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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

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Hypofractionated split-course versus standard radiotherapy in frail older patients with head and neck squamous-cell carcinoma (ELAN-RT trial): a non-inferiority, multicentre, open-label, randomised controlled trial.

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Hypofractionated radiotherapy for head and neck squamous cell carcinoma.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2025
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Radiotherapy: Beyond cancer….

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2025
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Exploiting Integrin-αVβ3 to Enhance Radiotherapy Efficacy in Medulloblastoma via Ferroptosis.

Current oncology (Toronto, Ont.)·2024
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Adapted EXTREME regimen in the first-line treatment of fit, older patients with recurrent or metastatic head and neck squamous cell carcinoma (ELAN-FIT): a multicentre, single-arm, phase 2 trial.

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Cetuximab versus methotrexate in first-line treatment of older, frail patients with inoperable recurrent or metastatic head and neck cancer (ELAN UNFIT): a randomised, open-label, phase 3 trial.

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Related Experiment Video

Updated: Jun 5, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
12:45

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer

Published on: February 12, 2022

[Rectal cancer: which initial strategy?].

Jean-Pierre Gérard1, Cécile Ortholan

  • 1Centre Antoine-Lacassagne, Département de Radiothérapie, Université Nice-Sophia-Antipolis, 06189 Nice Cedex 2. jean-pierre.gerard@nice.fnclcc.fr

La Revue Du Praticien
|January 5, 2011
PubMed
Summary
This summary is machine-generated.

Surgery is the primary treatment for rectal adenocarcinoma, with outcomes depending on tumor stage. Advanced tumors receive pre-operative chemo-radiation, leading to high cure rates and reduced need for permanent stoma.

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Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
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The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
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The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

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Last Updated: Jun 5, 2026

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Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction

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The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
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The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors

Published on: February 13, 2026

Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiation Oncology

Context:

  • Rectal adenocarcinoma treatment decisions are based on tumor stage after thorough patient evaluation.
  • Surgical intervention is the cornerstone of rectal cancer management.
  • Treatment planning involves informed patient consent.

Purpose:

  • To outline current treatment strategies for rectal adenocarcinoma based on tumor stage.
  • To highlight the efficacy of pre-operative chemo-radiation for advanced tumors.
  • To present outcomes regarding cure rates, stoma avoidance, and recurrence.

Summary:

  • Early-stage (T1-2) rectal adenocarcinoma is primarily treated with surgery.
  • Advanced-stage (T3-4) tumors often undergo pre-operative chemo-radiation, commonly using the CAP 50 regimen.
  • For inoperable cases, external beam radiation therapy with or without chemotherapy and 50 kV Contact X-ray can achieve high cure rates for early-stage tumors.

Impact:

  • Current treatment protocols achieve definitive cancer cures in approximately 60% of patients.
  • Approximately 75% of patients can avoid a permanent stoma after treatment.
  • Pelvic relapse rates are low, occurring in less than 6% of cases.