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Updated: Jun 5, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
N-(4-Methyl-phen-yl)benzamide.
This study details the molecular structure of a novel compound, C(14)H(13)NO, revealing specific dihedral angles between its aromatic rings and amide group. Molecules form chains via hydrogen bonds, offering insights into crystal packing.
Area of Science:
- Crystallography
- Organic Chemistry
- Molecular Structure
Background:
- The study investigates the structural characteristics of a novel organic compound, C(14)H(13)NO.
- Comparison with related benzamide derivatives highlights structural similarities and differences.
Purpose of the Study:
- To elucidate the precise three-dimensional molecular structure of C(14)H(13)NO.
- To analyze the spatial arrangement and interactions of its constituent functional groups.
Main Methods:
- Single-crystal X-ray diffraction was employed to determine the molecular and crystal structure.
- Analysis of bond parameters, dihedral angles, and intermolecular interactions.
Main Results:
- The compound C(14)H(13)NO exhibits specific dihedral angles: 63.41° between benzene and methylphenyl rings, and 20.5° between the amide group and the benzene ring.
- Intermolecular N-H⋯O hydrogen bonds link molecules into chains along the b-axis.
Conclusions:
- The determined structure provides a detailed understanding of the compound's conformation.
- The hydrogen bonding network significantly influences the crystal packing and overall molecular arrangement.
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