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Updated: Jun 5, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
N-(Biphenyl-4-ylcarbon-yl)-N'-(2-pyridylmeth-yl)thio-urea
Abstract:
In the title compound, C(20)H(17)N(3)OS, the dihedral angle between the benzene rings of the biphenyl fragment is 36.84 (9)°. The trans-cis geometry of the thio-urea unit is stabilized by intra-molecular N-H⋯O and N-H⋯N hydrogen bonds between the H atom of the cis thio-amide and the carbonyl O and pyridine N atoms, respectively. In the crystal structure, inter-molecular N-H⋯S hydrogen bonds form centrosymmetric dimers extending along the b axis.
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