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Updated: Jun 5, 2026

Facile Preparation of 4-Substituted Quinazoline Derivatives
Published on: February 15, 2016
2-Chloro-12-phenyl-6,7,8,9,10,11-hexa-hydro-cyclo-octa-[b]quinoline
Ayoob Bazgir1, Ali Mohammad Astaraki
1Department of Chemistry, Islamic Azad University, Dorood Branch, Dorood 688173551, Iran.
Abstract:
In the mol-ecule of the title compound, C(21)H(20)ClN, the quinoline group is nearly planar and is oriented at a dihedral angle of 77.21 (3)° with respect to the phenyl ring. The conformation of the cyclooctane ring is twist-boat. In the crystal structure, there are some weak π-π inter-actions [centroid-to-centroid distances of 3.7414 (11) and 3.8633 (12) Å] between the rings of the quinoline groups.
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