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Updated: Jun 5, 2026

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Published on: January 19, 2016
(E)-4-(4-Fluoro-styr-yl)benzoic acid
This study details a key intermediate compound, C(15)H(11)FO(2), crucial for synthesizing side-chain ligands used in polymeric liquid crystals. Its crystal structure reveals specific molecular arrangements stabilized by hydrogen bonding.
Area of Science:
- Materials Science
- Crystallography
- Organic Chemistry
Background:
- Polymeric liquid crystals are essential in advanced display technologies.
- Developing novel side-chain ligands is key to tuning liquid crystal properties.
- The synthesis of specific intermediates is critical for efficient ligand production.
Purpose of the Study:
- To characterize a novel intermediate compound, C(15)H(11)FO(2).
- To investigate the structural properties and bonding of this intermediate.
- To establish its utility in synthesizing ligands for polymeric liquid crystals.
Main Methods:
- Single-crystal X-ray diffraction was used to determine the molecular and crystal structure.
- Spectroscopic methods were employed for compound characterization.
- Synthetic routes were explored to confirm its role as an intermediate.
Main Results:
- The crystal structure of C(15)H(11)FO(2) was elucidated.
- The vinyl group was observed to be nearly coplanar with the aromatic rings.
- Intermolecular O-H⋯O hydrogen bonding was identified as a stabilizing factor in the crystal lattice.
Conclusions:
- C(15)H(11)FO(2) is a structurally defined and important intermediate for side-chain ligand synthesis.
- The observed planarity and hydrogen bonding influence the compound's properties and potential applications.
- This research provides a foundation for the development of new materials in liquid crystal technology.
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