Related Experiment Video
Updated: Jun 5, 2026

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
1-(2-Furo-yl)-3-(1-naphth-yl)thio-urea
Abstract:
In the title compound, C(16)H(12)N(2)O(2)S, the carbonyl-thio-urea group forms dihedral angles of 75.4 (1) and 13.1 (2)°, respectively, with the naphthalene ring system and furan ring. The mol-ecule adopts a trans-cis configuration with respect to the positions of the furoyl and naphthyl groups relative to the S atom across the thio-urea C-N bonds. This geometry is stabilized by an N-H⋯·O intra-molecular hydrogen bond. In the crystal structure, mol-ecules are linked by N-H⋯S hydrogen bonds, forming centrosymmetric dimers which are inter-linked through C-H⋯π inter-actions.
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