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Updated: Jun 5, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
Published on: November 23, 2016
N-(2,6-Dimethyl-phen-yl)-2-methyl-benzamide
Abstract:
In the title mol-ecule, C(16)H(17)NO, the N-H and C=O groups are in the anti-periplanar conformation that has been observed in related compounds. Furthermore, the conformation of the C=O group with respect to the methyl substituent in the 2-methyl-phenyl ring is syn, as has also been observed in related structures. The amide group makes dihedral angles of 50.3 (3) and 64.6 (3)° with the 2-methyl-phenyl and 2,6-dimethyl-phenyl rings, respectively, while the angle between the planes of the two rings is 14.26 (7)°. The mol-ecules are packed into chains via N-H⋯O hydrogen bonds. An intramolecular C-H⋯O hydrogen bond is also observed.
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