Related Experiment Video
Updated: Jun 5, 2026

07:10
Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
Published on: January 7, 2019
What do deaf high school students know about HIV?
Marjorie F Goldstein1, Elizabeth A Eckhardt, Patrice Joyner-Creamer
1National Development Research Institute, Inc., New York, NY 10010, USA. goldstein@ndri.org
Summary
Deaf adolescents using American Sign Language (ASL) have limited HIV knowledge. School-based HIV education is crucial for this population to improve understanding and reduce risks.
Area of Science:
- Public Health
- Adolescent Health
- Sign Language Communication
Background:
- Deaf adolescents using American Sign Language (ASL) are vulnerable to HIV, similar to hearing peers.
- Traditional HIV information sources are inaccessible to ASL-dependent deaf adolescents.
- Limited data exists on HIV knowledge and risk behaviors within this demographic.
Purpose of the Study:
- To develop and administer a comprehensive HIV knowledge and risk survey specifically for deaf adolescents.
- To assess the current level of HIV knowledge among deaf adolescents using ASL.
- To identify factors associated with HIV knowledge in this population.
Main Methods:
- A survey was developed and administered using laptop computers in American Sign Language (ASL).
- The study included 700 deaf adolescent participants from high schools across the United States.
- A reliable knowledge scale (Cronbach's α = .83) with 14 items was used to assess HIV knowledge.
Main Results:
- Participants answered approximately half of the 14 HIV knowledge items correctly (mean = 7.2, median = 7.0).
- Multivariable analysis indicated a strong correlation between HIV knowledge scores and receiving information in school.
- Significant gaps in HIV knowledge were identified among the surveyed deaf adolescents.
Conclusions:
- Deaf adolescents demonstrate a need for improved HIV knowledge.
- School-based HIV education is a critical factor in enhancing knowledge for deaf adolescents.
- Linguistically and culturally appropriate HIV prevention education in schools is essential for this population.
Related Concept Videos
Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Immunodeficiency Diseases
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
There are three main causes of immunodeficiency disorders...
Retrovirus Life Cycles
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...
Genital Herpes
Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Learning Disabilities
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
Dyslexia
Dyslexia is a...
Herpes
Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
