Related Experiment Video
Updated: Jun 5, 2026
06:25
Analysis of Simian Immunodeficiency Virus-specific CD8+ T-cells in Rhesus Macaques by Peptide-MHC-I Tetramer Staining
Published on: December 23, 2016
Camptomelia in a rhesus macaque (Macaca mulatta)
Kelly Hopper1, Pablo Morales, Anapatricia Garcia
1The Mannheimer Foundation, Homestead, Florida, USA. khopper@mannheimerfoundation.org
Summary
A young rhesus macaque presented with bowed long bones, a condition known as idiopathic camptomelia. Further diagnostics ruled out common metabolic bone diseases, leading to this rare diagnosis.
Area of Science:
- Veterinary Medicine
- Primate Research
- Skeletal Dysplasias
Background:
- Idiopathic camptomelia, or bowing of long bones, is a rare skeletal dysplasia.
- In humans, it is often linked to genetic mutations affecting epiphyseal development and associated with other abnormalities.
Observation:
- An 8.5-month-old female rhesus macaque exhibited forearm bowing, initially perceived as a lump.
- Radiography confirmed bowing of long bones without signs of pain.
- No similar cases were observed in the colony.
Findings:
- Comprehensive diagnostics, including blood chemistry, hemogram, and vitamin D profiling, were within normal limits.
- Bone biopsies were unremarkable for the animal's age.
- Fluorine levels in the water supply were also normal.
Implications:
- The diagnosis of idiopathic camptomelia in this macaque highlights its occurrence outside of known genetic syndromes.
- This case provides valuable insight into rare skeletal abnormalities in non-human primates.
- Further research may elucidate potential genetic or environmental factors contributing to this condition in macaques.
