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Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
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Related Experiment Video

Updated: Jun 5, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Postpartum depression: an essential overview for the practitioner.

Sarah J Breese McCoy1

  • 1Department of Physiology, Oklahoma State University Center for Health Sciences and College of Osteopathic Medicine and Surgery, Tulsa, OK 74107, USA. sjmccoy98@aol.com

Southern Medical Journal
|January 6, 2011
PubMed
Summary

Postpartum depression (PPD) affects 13% of women, impacting maternal and infant health. Early screening and treatment by healthcare providers are crucial for positive outcomes.

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Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
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Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

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Last Updated: Jun 5, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants

Published on: June 13, 2021

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents
07:30

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Published on: June 10, 2013

Area of Science:

  • Obstetrics and Gynecology
  • Psychiatry
  • Public Health

Background:

  • Postpartum depression (PPD) is a common yet underdiagnosed condition affecting approximately 13% of mothers.
  • PPD presents significant health risks for both mother and child, necessitating effective screening and management strategies.
  • Potential etiologies include hormonal fluctuations, postpartum hypothyroidism, sleep deprivation, and psychosocial stressors.

Purpose of the Study:

  • To highlight the prevalence and impact of postpartum depression.
  • To emphasize the importance of accessible screening tools for PPD.
  • To underscore the role of healthcare providers in identifying and managing PPD.

Main Methods:

  • Review of current literature on PPD prevalence, causes, and treatments.
  • Discussion of the utility of self-administered screening tools.
  • Exploration of screening opportunities within obstetric, pediatric, and general practice settings.

Main Results:

  • Effective screening tools for PPD are readily available.
  • Various factors contribute to PPD, including hormonal changes and lifestyle stressors.
  • Healthcare providers are uniquely positioned to facilitate PPD identification and referral.

Conclusions:

  • Increased screening for postpartum depression is essential due to underdiagnosis rates.
  • Obstetricians, pediatricians, and general practitioners can significantly improve maternal and child well-being by identifying and managing PPD.
  • Integrated care approaches involving screening, treatment, and referrals are vital for addressing PPD effectively.