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Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Risperidone induced tardive dyskinesia - a case report
O V Vasudevan1, Denzil A Pinto, P S Gopinath
1O.V. VASUDEVAN, M.B.B.S., Junior Resident, Department of Psychiatry, Fr. Muller's Medical College, Mangalore - 575 002.
Indian Journal of Psychiatry
|January 6, 2011
Summary
This case report highlights tardive dyskinesia (TD) in a patient treated with risperidone, a serotonin-dopamine antagonist. Clinicians should remain vigilant for TD development, even with newer antipsychotics.
Area of Science:
- Neuroscience
- Psychiatry
- Pharmacology
Background:
- Risperidone, a second-generation antipsychotic, acts as a serotonin-dopamine antagonist.
- While generally considered to have a lower risk of tardive dyskinesia (TD) compared to older antipsychotics, TD has been reported with risperidone.
- Tardive dyskinesia is a serious neurological side effect characterized by involuntary movements.
Purpose of the Study:
- To report a case of tardive dyskinesia (TD) induced by risperidone.
- To increase awareness among clinicians regarding the potential for TD with risperidone treatment.
- To discuss risk factors associated with TD development in this specific case.
Main Methods:
- Case report presentation.
- Review of patient's medical history, including diagnosis, medication, and symptom onset.
- Identification of potential risk factors for tardive dyskinesia.
Main Results:
- A 56-year-old female with paranoid schizophrenia developed bucco-oro-masticatory involuntary movements after 1 year of risperidone treatment (8 mg/day).
- The patient presented with several risk factors for TD, including advanced age, female sex, concurrent use of anticholinergic drugs, and prior neuroleptic-induced parkinsonism.
- This case illustrates that even atypical antipsychotics like risperidone can induce TD.
Conclusions:
- Clinicians must be aware of the potential for tardive dyskinesia (TD) in patients treated with risperidone.
- Risk factors such as age, sex, anticholinergic use, and prior parkinsonism may increase susceptibility to TD with risperidone.
- Vigilance and monitoring for TD are crucial in patients receiving risperidone, despite its perceived safety profile.
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