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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

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Related Experiment Video

Updated: Jun 5, 2026

Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats
06:22

Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats

Published on: April 14, 2023

Uterus transplantation: on the edge.

Giuseppe Del Priore1, Stefan Schlatt, Robert Wagner

  • 1Indiana University, Simon Cancer Center, Department of Ob-Gyn, Indianapolis, Indiana 46202, USA. gdelprio@IUPIU.edu

Seminars in Reproductive Medicine
|January 6, 2011
PubMed
Summary

Uterus transplantation is nearing human trials for infertility caused by uterine factors. This procedure offers a potential solution, with risks comparable to other high-risk pregnancies, requiring further research for clinical application.

More Related Videos

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
06:43

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model

Published on: October 9, 2018

Related Experiment Videos

Last Updated: Jun 5, 2026

Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats
06:22

Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats

Published on: April 14, 2023

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model
06:43

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model

Published on: October 9, 2018

Area of Science:

  • Reproductive medicine
  • Transplantation surgery

Background:

  • Absolute uterus factor infertility presents a significant challenge for women unable to carry a pregnancy.
  • Uterus transplantation is being explored as a potential solution to address this unmet medical need.

Purpose of the Study:

  • To evaluate the feasibility and potential of uterus transplantation for treating absolute uterus factor infertility.
  • To discuss the implications and requirements for moving uterus transplantation towards clinical trials.

Main Methods:

  • Review of extensive collaborative research, including animal studies and advancements in transplantation medicine.
  • Analysis of immune suppression protocols relevant to uterus transplantation.

Main Results:

  • Demonstrated apparent feasibility of uterus transplantation through cumulative research efforts.
  • Risk assessment indicates comparability to other high-risk pregnancies.

Conclusions:

  • Uterus transplantation is a viable option for absolute uterus factor infertility, moving closer to human trials.
  • Continued research and support are essential for the clinical application of uterus transplantation.