Related Experiment Video
Updated: Jun 5, 2026

09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Acute ischemic stroke management: medical management.
Kevin M Barrett1, James F Meschia
1Department of Neurology, Mayo Clinic Florida, Jacksonville, Florida 32224, USA. Barrett.kevin@mayo.edu
Seminars in Neurology
|January 6, 2011
Summary
Rapid evaluation is key for suspected stroke patients. This review covers urgent assessment and evidence-based treatments like intravenous thrombolysis for acute ischemic stroke.
Area of Science:
- Neurology
- Emergency Medicine
- Cardiovascular Research
Background:
- Prompt evaluation is crucial for suspected stroke patients.
- Identifying symptom onset time and performing focused examinations are vital.
- Ancillary tests aid in delivering acute stroke therapies.
Purpose of the Study:
- To review the fundamentals of urgent stroke evaluation.
- To highlight evidence-based acute ischemic stroke therapies.
- To discuss specific treatments including intravenous thrombolysis and management of wake-up strokes.
Main Methods:
- Review of randomized clinical trials.
- Emphasis on urgent stroke evaluation protocols.
- Discussion of acute ischemic stroke therapies.
Main Results:
- Intravenous thrombolysis is a key acute ischemic stroke therapy.
- Glucose and blood pressure management are critical.
- External ultrasound and wake-up stroke treatments are discussed.
Conclusions:
- Urgent and focused evaluation is fundamental for stroke management.
- Evidence-based therapies, including thrombolysis, improve outcomes.
- Further research and discussion on adjunct therapies and specific patient populations are warranted.
Related Concept Videos
Acute Coronary Syndrome IV: Interprofessional Care
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Angina IV: Management
IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
Ischemic Stroke ll: Pathophysiology
An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Ischemic Stroke l: Introduction
Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Myocarditis III: Medical Management
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
Atherosclerosis III: Management
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
