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Published on: February 15, 2022
[Effect of nerve growth factor on the visual evoked potential of rats pretreated by CS2]
1Department of Basic Medicine, Second Military Medical University, Shanghai 200433, China.
Aim:
To study the therapeutic effect of NGF to rats with newly CS2 deranged.
Methods:
The model of rats with deranged visual nerve was made by CS2 (i.p) for three weeks. Rats were then treated with different dosages of NGF for three weeks, and the changes of visual evoked potential were determined.
Results:
The latency of PREP and FEP shortened significantly vs control after treatment for 10 and 20 days.
Conclusion:
NGF can improve the conductivity of visual with dose-effect relationship, suggesting that NGF has a significant therapeutic effect on the deranged visual nerve.
