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Vaccination coverage and risk factors for incomplete vaccination in children with recurrent wheeze

E Ozkaya1, N Cambaz, L D Kolsuz

  • 1Department of Pediatrics, Vakıf Gureba Education and Research Hospital, Istanbul, Turkey. minozkaya@yahoo.com

Allergologia Et Immunopathologia
|January 7, 2011
PubMed

Insights

Children with recurrent wheeze are at high risk for incomplete immunisation. This study highlights the need for ensuring adequate vaccination for infants experiencing recurrent wheezing episodes.

Area of Science:

  • Pediatric Pulmonology
  • Immunology
  • Public Health

Background:

  • Recurrent wheeze in early childhood is a common respiratory issue.
  • Immunisation status is crucial for preventing infectious diseases in infants.
  • The relationship between recurrent wheeze and vaccination adherence requires further investigation.

Purpose of the Study:

  • To assess the impact of recurrent wheeze on childhood immunisation rates.
  • To determine if children with recurrent wheeze are less likely to complete their vaccination schedules.
  • To identify specific vaccines potentially affected by recurrent wheeze.

Main Methods:

  • A case-control study comparing 288 children with recurrent wheeze to 190 controls under three years old.
  • Analysis of vaccination charts against the National Immunisation Schedule.
  • Parental questionnaires collected supplementary data.

Main Results:

  • Children with recurrent wheeze showed significantly lower vaccination rates for BCG, hepatitis B, Hib, and MMR.
  • An inverse relationship was observed between the frequency of wheezing episodes and the number of vaccine doses received.
  • The odds of incomplete vaccination were substantially higher (OR 10.6) in children with recurrent wheeze.

Conclusions:

  • Infants under three years old experiencing recurrent wheeze face a significant risk of incomplete immunisation.
  • Targeted interventions are necessary to ensure adequate vaccination coverage in this vulnerable pediatric population.
  • Addressing vaccination gaps in children with recurrent wheeze is essential for public health.
Abstract

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