Vertebral artery dissection presented as lateral medullary syndrome in a patient with migraine: a case report

Ju-Chun Yen1, Lung Chan, Yen-Jun Lai

  • 1Section of Neurology, Department of Internal Medicine Far-Eastern Memorial Hospital, Taipei, Taiwan.

Abstract

Insights

Migraine attacks may predispose arteries to dissection, potentially causing ischemic stroke. This case highlights a link between basilar-type migraine and vertebral artery dissection, suggesting vessel wall changes as a possible mechanism.

Area of Science:

  • Neurology
  • Vascular Neurology
  • Neuroscience

Background:

  • Migraine and intracranial artery dissection are rare causes of ischemic stroke.
  • The mechanism linking migraine to intracranial artery dissection remains unclear.
  • Repeated migraine attacks may increase artery vulnerability to dissection.

Observation:

  • A 42-year-old female with a 20-year history of basilar-type migraine presented with dizziness.
  • Neurological examination revealed lateral medullary syndrome.
  • Brain MRI confirmed acute infarction in the left lateral medulla oblongata.

Findings:

  • Cerebral angiography identified dissection of the left distal vertebral artery.
  • The patient received aspirin for secondary stroke prevention and topiramate for migraine prophylaxis.
  • This case suggests a potential association between migraine and vertebral artery dissection.

Implications:

  • The findings suggest that vessel wall edematous changes from repeated migraine attacks may lead to dissection.
  • This proposed mechanism involves sudden or unusual vessel stretching.
  • Further research is needed to elucidate the exact mechanism of migraine-related intracranial artery dissection.

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