[Advanced research in Sclera collagen cross-linking treating progressive myopia]

Area of Science:

• Ophthalmology
• Biomaterials Science
• Tissue Engineering

Context:

• Progressive myopia is characterized by changes in scleral collagen structure and biomechanics.
• Current treatments for myopia progression have limitations.
• Scleral collagen cross-linking is an emerging therapeutic strategy.

Purpose:

• To review the characteristics of scleral collagen in progressive myopia.
• To discuss traditional myopia treatments.
• To explore the potential of scleral collagen cross-linking therapy.

Summary:

• Collagen cross-linking involves forming covalent bonds within or between collagen molecules, enhancing fiber tension and stability.
• Research indicates that cross-linking scleral collagen significantly improves biomechanical rigidity.
• This enhancement may serve as a novel approach to strengthen scleral tissue and inhibit myopia progression.

Impact:

• Scleral collagen cross-linking presents a promising therapeutic avenue for managing and potentially reversing progressive myopia.
• Strengthening the sclera could offer a new strategy to prevent vision impairment associated with myopia.
• This review provides insights into the scientific basis and therapeutic potential of scleral cross-linking.