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Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells
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[Gene and cell therapy for primary immunodeficiency diseases]

Makoto Otsu1

  • 1Division of Stem Cell Therapy, Center for Stem Cell Biology and Regenerative Medicine.

Nihon Rinsho Men'Eki Gakkai Kaishi = Japanese Journal of Clinical Immunology
|January 8, 2011
PubMed
Summary

Stem cell gene therapy offers a promising curative treatment for primary immunodeficiency diseases (PID), including severe combined immunodeficiency (SCID). Current challenges include potential leukemogenesis risks, with future directions exploring induced pluripotent stem cells.

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