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Updated: Jun 5, 2026

Cholesterol Efflux Assay
Published on: March 6, 2012
Quinazolin-4(3H)-ones capable of upregulating the expression of endogenous apolipoprotein A-1
Jianhui Wu1, Ming Zhao, Shiqi Peng
1Capital Medical University, College of Pharmaceutical Sciences, Beijing 100069, PR China.
Abstract:
An application claims non-naturally occurring upregulators of apolipoprotein A-I (ApoA-l) quinazolin-4(3H)-ones. The claimed quinazolin-4(3H)-ones are efficacious in upregulating the expression of endogeneous ApoA-l, and can potentially treat and prevent cardiovascular disease and related disease states, including cholesterol or lipid-related disorders, such as atherosclerosis. This application of Resverlogix Corp. increases the diversity of quinazolin-4(3H)-ones capable of upregulating the expression of endogeneous ApoA-l.
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