Inter-subunit interactions in erythroid and non-erythroid spectrins

Xiuli An1, Xinhua Guo, Yang Yang

  • 1Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA. xan@nybloodcenter.org

Summary

Spectrin protein interactions are crucial for cell structure. This study reveals how specific repeating units in erythroid and brain spectrin subunits assemble into dimers, highlighting differences in interaction strength and evolutionary divergence.

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