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Updated: Jun 5, 2026

A Gaze-Contingent Display Framework for Perceptual Learning Research with Simulated Central Vision Loss
Published on: April 11, 2025
Impairment in processing visual information at the pre-attentive stage in patients with a major depressive disorder:
Xiaohui Qiu1, Xiuxian Yang, Zhengxue Qiao
1Department of Medical Psychology, Public Health Institute of Harbin Medical University, Heilongjiang Province, China.
Abstract:
We compared the pre-attentive processing in patients with a major depressive disorder (MDD) and matched healthy controls as indexed by the visual mismatch negativity (vMMN) elicited by exposure duration of visual stimuli randomly presented on both peripheral visual fields. To obtain the memory-comparison-based visual MMN, the role of standard and deviant stimuli was reversed in separate blocks. Compared with healthy participants, MDD patients exhibited decreased MMN amplitudes of long duration deviant only and this deficit was not correlated with the depression severity. These data suggests functional impairment of pre-attentive basic visual information processing in MDD patients.
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