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MADGene: retrieval and processing of gene identifier lists for the analysis of heterogeneous microarray datasets

Daniel Baron1, Audrey Bihouée, Raluca Teusan

  • 1INSERM U915, IRT-UN, University of Nantes, France.

Bioinformatics (Oxford, England)
|January 11, 2011
PubMed
Abstract

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...