Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Appendicitis

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Appendicitis-II: Diagnostic Studies and Management

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...

Diverticular Disease of the Colon

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

Chronic Pancreatitis II: Pathophysiology

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Osteonecrosis (avascular necrosis) in inflammatory bowel disease: an extraintestinal clinical feature, not caused by corticosteroids.

European journal of gastroenterology & hepatology·2024

Same author

Collagenous colitis associated with novel sprue-like intestinal diseases.

Gastroenterology and hepatology from bed to bench·2023

Same author

Segmental Colitis Associated with Diverticulosis (SCAD).

Current gastroenterology reports·2023

Same author

Challenges in gluten-free diet in coeliac disease: Prague consensus.

European journal of clinical investigation·2017

Same author

Correction: Heterogeneity in Comparisons of Discontinuation of Tumor Necrosis Factor Antagonists in Rheumatoid Arthritis-A Meta-Analysis.

PloS one·2017

Same author

Segmental colitis associated diverticulosis syndrome.

World journal of gastroenterology·2016

Same journal

Lessons from extended induction and practical evidence for improving tofacitinib therapy in ulcerative colitis.

World journal of gastroenterology·2026

Same journal

Small animal <i>ex vivo</i> machine perfusion of the liver: A comprehensive literature review.

World journal of gastroenterology·2026

Same journal

Comparable remission and health care use in real-world inflammatory bowel disease patients initiating originator biologics <i>vs</i> biosimilars.

World journal of gastroenterology·2026

Same journal

Diagnosis and management of metabolic dysfunction-associated steatohepatitis in patients with chronic hepatitis B infection.

World journal of gastroenterology·2026

Same journal

Simultaneous treatment of concomitant achalasia coexisting with epiphrenic diverticulum: The practice of submucosal tunneling technique.

World journal of gastroenterology·2026

Same journal

Lianhe Xiaozhi ointment ameliorates metabolic dysfunction-associated steatotic liver disease <i>via</i> peroxisome proliferator-activated receptor alpha pathway activation.

World journal of gastroenterology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Duplicated appendix complicated by appendiceal cancer.

World Journal of Gastroenterology

|January 11, 2011

Summary

This summary is machine-generated.

A rare case of a duplicated appendix in an adult presented with appendicitis and cancer. Early diagnosis of congenital intestinal duplications is crucial for preventing severe health issues.

Keywords:

Appendiceal cancer Bifid appendix Congenital duplication.Duplicated appendix

More Related Videos

Application of Robot-assisted Pancreaticobiliary Junction Resection in Benign Duodenal Tumors

Application of Robot-assisted Pancreaticobiliary Junction Resection in Benign Duodenal Tumors

Published on: December 20, 2024

Related Experiment Videos

Last Updated: Jun 5, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

Application of Robot-assisted Pancreaticobiliary Junction Resection in Benign Duodenal Tumors

Application of Robot-assisted Pancreaticobiliary Junction Resection in Benign Duodenal Tumors

Published on: December 20, 2024

Area of Science:

Gastroenterology
Surgical Pathology
Congenital Abnormalities

Background:

Appendicitis is a common surgical emergency.
Congenital intestinal duplications are rare anomalies.
Adult presentation of appendiceal pathology can be diverse.

Observation:

A 37-year-old male presented with symptoms of acute appendicitis.
Laparotomy revealed a duplicated appendix.
One lumen showed acute appendicitis with a peri-appendicular abscess.
The second lumen contained a localized appendiceal cancer.

Findings:

The patient had a rare congenital duplication of the appendix.
Appendicitis and appendiceal cancer occurred simultaneously in separate lumens.
This case highlights a complex presentation of appendiceal disease.

Implications:

Congenital intestinal duplications require high clinical suspicion in adults.
Failure to recognize duplications can lead to delayed diagnosis and complications.
This case underscores the importance of thorough surgical evaluation for unusual abdominal presentations.