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Mesoappendiceal and periappendiceal lesions

Badr AbdullGaffar1, Tasnim Keloth

  • 1Histopathology Department, Dubai Hospital, Dubai, United Arab Emirates. gaffarbadr@hotmail.com

Pathology, Research and Practice
|January 14, 2011
PubMed

Insights

Mesoappendiceal lesions are rare but can be clinically significant. Careful pathological examination of appendectomy specimens is crucial for identifying these often-overlooked findings, including infections and tumors.

Area of Science:

  • Gastroenterology
  • Pathology
  • Surgical Pathology

Background:

  • Lesions of the mesoappendix are uncommon and frequently overlooked during routine pathological examination of appendectomy specimens.
  • While often benign and incidental, mesoappendiceal lesions can encompass a range of infectious, tumor-like, and neoplastic conditions with clinical implications.

Purpose of the Study:

  • To highlight the importance of thorough gross examination of the mesoappendix in appendectomy specimens.
  • To determine the spectrum and frequency of mesoappendiceal and periappendiceal lesions.

Main Methods:

  • Retrospective review of 4371 appendectomy specimens over a four-year period.
  • Detailed gross examination and sectioning of the mesoappendix were emphasized.

Main Results:

  • Eight cases (0.18%) of mesoappendiceal or periappendiceal lesions were identified.
  • Findings included benign entities (e.g., reactive lymph nodes, ectopic decidua), an inflammatory fibroid tumor, and clinically significant infections (tuberculosis, schistosomiasis).
  • Lesions were more prevalent in young adult males (male to female ratio 7:1).

Conclusions:

  • Thorough pathological examination of the mesoappendix is essential for detecting rare but potentially significant lesions.
  • Increased awareness and meticulous grossing techniques can improve the identification of these findings, aiding patient management.

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