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Using Mouse Oocytes to Assess Human Gene Function During Meiosis I
Published on: April 10, 2018
Why is the house mouse karyotype so variable?
1Michael Nachman is at the Section of Genetics and Development, Biotechnology Building, Cornell University, Ithaca, NY 14853, USA.
Abstract:
rates of robertsonian chromosomal evolution in the Western European house mouse are about two orders of magnitude greater than for most other mammals. This has resulted in a remarkable diversity of karyotypic races in a very short period of time. Recent studies are beginning to shed light on the relative contributions of mutation, drift, selection and meiotic drive in producing this pattern.
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