Kimura disease in the parotid gland

Area of Science:

• Dermatology and Pathology

Background:

• Kimura disease (KD) is a rare, chronic inflammatory condition predominantly affecting Asian populations.
• It is histopathologically defined by lymph-folliculoid granuloma with significant eosinophilic infiltration.
• KD typically manifests in the head and neck region, particularly the preauricular area.

Observation:

• This article presents a case of Kimura disease in a 14-year-old male patient.
• The affected area was the left parotid region.
• The presentation included clinical, radiologic, surgical, and pathological findings.

Findings:

• Histopathological examination revealed lymph-folliculoid granuloma consistent with Kimura disease.
• The mass and surrounding tissues showed infiltration by eosinophils.
• Associated findings may include peripheral blood eosinophilia and elevated serum immunoglobulin E levels.

Implications:

• This case highlights the importance of considering Kimura disease in the differential diagnosis of head and neck masses, especially in endemic populations.
• Comprehensive evaluation involving clinical, imaging, and histopathological data is crucial for accurate diagnosis.
• Understanding the diverse presentations of KD aids in timely and appropriate management.