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Related Experiment Video

Updated: Jun 5, 2026

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Published on: October 10, 2025

Association between bacterial vaginosis and preterm delivery.

T R Das¹, S Jahan, S R Begum

¹Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.

Mymensingh Medical Journal : MMJ

|January 18, 2011

Summary

Bacterial vaginosis (BV) is common in women and linked to preterm delivery. This study found BV significantly increases the risk of premature birth in pregnant women.

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Area of Science:

Obstetrics
Microbiology
Reproductive Health

Background:

Bacterial vaginosis (BV) is a frequent condition in women of reproductive age.
BV prevalence is notable in obstetric populations, contributing to preterm delivery risks.

Purpose of the Study:

To investigate the association between bacterial vaginosis and preterm delivery.
To determine if BV is a risk factor for premature birth.

Main Methods:

A study included 100 pregnant women (15-35 years) between 28-36 weeks gestation with suspected BV.
Participants were categorized into BV-positive (37) and BV-negative (63) groups using Amsel clinical criteria.
Demographic and socioeconomic factors showed no significant differences between groups.

Main Results:

A significantly higher percentage of BV-positive women experienced preterm delivery (73%) compared to BV-negative women (25.4%).
Mean gestational age at delivery was significantly lower in the BV-positive group (35.24 ± 2.33 weeks) versus the BV-negative group (37.49 ± 2.53 weeks).

Conclusions:

Abnormal bacterial colonization, characteristic of bacterial vaginosis, is strongly associated with preterm delivery.
BV is a significant risk factor for premature birth in pregnant women.