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Related Experiment Video

Updated: Jun 5, 2026

Imaging Subcellular Structures in the Living Zebrafish Embryo
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Imaging Subcellular Structures in the Living Zebrafish Embryo

Published on: April 2, 2016

Zebrafish as a good vertebrate model for molecular imaging using fluorescent probes.

Sung-Kyun Ko1, Xiaoqiang Chen, Juyoung Yoon

  • 1Center for Biofunctional Molecules, Department of Chemistry, Yonsei University, Seoul 120-749, Korea.

Chemical Society Reviews
|January 18, 2011
PubMed
Summary

Researchers are advancing whole-animal fluorescent imaging using zebrafish. This review highlights new fluorescent probes, including fluorescent proteins, synthetic dyes, and quantum dots, for detailed biological effect analysis in live zebrafish.

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Area of Science:

  • Biomedical Imaging
  • Molecular Biology
  • Zebrafish Research

Background:

  • Fluorescent probes are crucial for monitoring biomolecules and species in vitro and in vivo.
  • A shift towards whole-animal imaging is emerging to better understand analyte biological effects.
  • Zebrafish offer significant advantages for live vertebrate imaging.

Purpose of the Study:

  • To review recent advancements in live zebrafish imaging.
  • To highlight the application of various fluorescent probes in zebrafish models.
  • To discuss the potential of these techniques for detailed biological analysis.

Main Methods:

  • Review of current literature on fluorescent probe development and application.
  • Focus on fluorescent proteins, synthetic fluorescent dyes, and quantum dots.

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Last Updated: Jun 5, 2026

Imaging Subcellular Structures in the Living Zebrafish Embryo
11:19

Imaging Subcellular Structures in the Living Zebrafish Embryo

Published on: April 2, 2016

Fluorescence Labeling to Visualize Low-Expressed Proteins in Zebrafish
09:38

Fluorescence Labeling to Visualize Low-Expressed Proteins in Zebrafish

Published on: January 24, 2025

Visualization of Cellular Electrical Activity in Zebrafish Early Embryos and Tumors
08:55

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  • Analysis of techniques for live zebrafish imaging.

    • Main Results:

    • Identification of key fluorescent probe types suitable for zebrafish imaging.
    • Demonstration of progress in achieving detailed biological insights through whole-animal imaging.
    • Highlighting the versatility and advantages of zebrafish as a model organism.

    Conclusions:

    • Live zebrafish imaging with advanced fluorescent probes offers powerful insights into biological processes.
    • Fluorescent proteins, synthetic dyes, and quantum dots are key tools for this modality.
    • This approach is pivotal for understanding the in vivo biological effects of various species.