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Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus
Published on: June 6, 2025
Constituents of cultivated Agaricus blazei
Yumi Ueguchi1, Katsuyoshi Matsunami, Hideaki Otsuka
1Department of Pharmacognosy, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan.
Abstract:
Two phenylhexane derivatives (1, 2), benzoylergostane (3), N-benzoyl-L-leucine methyl ester (4), two known ergostanes, and highly degraded incisterol were isolated from fruit bodies of Agaricus blazei. Compound 3 exhibited strong cytotoxicity toward HepG2 cells (IC(50) = 6.0 ± 0.33 μM).
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