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Source and Route of Pyrrolizidine Alkaloid Contamination in Tea Samples
Published on: September 28, 2022
[Toxic hepatitis triggered by green tea]
Johan Rohde1, Claire Jacobsen, Hans Kromann-Andersen
1Medicinsk Afdeling, Glostrup Hospital, Denmark. johan.rohde@gmail.com
Abstract:
Green tea is associated with various beneficial health effects, but several cases of hepatotoxic side effects have been reported. We present the first Danish case of toxic hepatitis following the consumption of 4-6 cups of green tea per day for six months. Green tea's main chemical component is epigallocatechin gallate (EGCG). Animal studies have shown that EGCG accumulated in the liver is most toxic when consumed fasting and that it causes greater hepatotoxicity upon repeated administration. Green tea hepatotoxicity should be kept in mind and cases are notifiable to the food authorities.
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