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GABA withdrawal syndrome: a model of the epilepsia partialis continua
M Kunimoto1, T Tanaka, H Fukuda
1Department of Neurosurgery, Asahikawa Medical College.
The Japanese Journal of Psychiatry and Neurology
|June 1, 1990
Abstract:
After the chronic infusion of GABA into the cortex of baboon Papio Papio, a sudden stop of the infusion provoked cortical epileptic discharges around the infused area. And the baboon exhibited partial epilepsy for about 3 days. The result suggested that GABA withdrawal syndrome should be a good model not only to understand the mechanism of epilepsia partialis continua but also partial epilepsy with a circumscribed cortical focus.