Related Experiment Video
Updated: Jun 5, 2026

Microfluidics in Assessing Platelet Function
Published on: November 8, 2024
[Inhibitory effect of TBN on platelet aggregation in rabbit]
Chang-Lin Xu1, Lu-Chen Shan, Ye-Wei Sun
1Institute of New Drug Research, Jinan University, Guangzhou 510632, China. xucling19820813@126.com
Objective:
To investigate the inhibitory effect of TBN on rabbit platelet aggregation in vitro and in vivo, and compare with tetramethylpyrazine (TMP).
Methods:
To seek out the maximum of platelet aggregation (expressed in percentage) within 5 minutes which was induced by ADP, PAF and AA according to the Born turbidimetric method with a Platelet-Aggregometer.
Results:
TBN significantly inhibited platelet aggregation induced by ADP, PAF and AA both in vitro and in vivo. TBN was more active than TMP.
Conclusion:
TBN has significant activity inhibiting platelet aggregation induced by ADP, PAF and AA in vitro and in vivo.
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