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Structured exercise does not stabilize cognitive function in individuals with mild cognitive impairment residing in a
Lindsay A Miller1, Mary Beth Spitznagel, Susan Busko
1Department of Psychology, Kent State University, Kent Hall, Kent, Ohio 44242, USA.
The International Journal of Neuroscience
|January 20, 2011
Summary
Structured exercise programs did not improve cognition in individuals with mild cognitive impairment (MCI). While cardiovascular fitness improved, cognitive function declined, suggesting exercise may be more beneficial before MCI onset.
Area of Science:
- Neurology
- Gerontology
- Exercise Science
Background:
- Cognitive benefits of exercise are known in healthy older adults.
- No studies have assessed exercise in mild cognitive impairment (MCI) in structured facilities.
- MCI is a precursor to Alzheimer's disease, necessitating research into interventions.
Purpose of the Study:
- To investigate the cognitive effects of a 6-month structured exercise program in individuals with MCI.
- To determine if formal exercise can enhance brain function in this population.
Main Methods:
- Thirty-one participants with MCI underwent baseline and 6-month follow-up assessments.
- Neuropsychological testing and cardiovascular fitness measures were utilized.
- A structured program combining aerobic and resistance training was implemented.
Main Results:
- Cardiovascular fitness significantly improved in the MCI participants.
- No significant improvements in cognitive function were observed.
- Performance declined on several tests sensitive to Alzheimer's disease progression.
Conclusions:
- Formal exercise programs may not benefit cognitive function after the onset of MCI.
- Exercise might be more effective in preventing cognitive decline before MCI develops.
- Further research is needed to understand exercise's role in MCI and Alzheimer's disease.
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