Related Experiment Videos
[Non-invasive study of hemodynamics in peripheral arteries by pulsed Doppler associated with bidimensional
Insights
This study validates a 2D-echography and range-gated Doppler system for measuring peripheral artery blood flow. The system accurately calculates internal diameter, blood flow velocity, and blood flow in arteries like the carotid and femoral.
Area of Science:
- Vascular Ultrasound
- Doppler Echocardiography
- Hemodynamics
Context:
- Accurate measurement of peripheral artery hemodynamics is crucial for diagnosing vascular diseases.
- Existing methods may have limitations in precision and reproducibility.
- 2D-echography and range-gated Doppler offer a potential non-invasive solution.
Purpose:
- To validate a combined 2D-echography and range-gated Doppler system for measuring internal diameter and instantaneous blood flow velocity in peripheral arteries.
- To assess the system's accuracy in calculating blood flow (cross-sectional area * mean velocity).
- To evaluate the intra-observer and inter-observer reproducibility of diameter and velocity measurements.
Summary:
- The system visualizes arteries (common carotid, femoral, humeral) using echography to determine diameter and cross-sectional area.
- A range-gated Doppler system, fixed at a 38.5-degree angle, measures instantaneous blood flow velocity.
- In vitro and in vivo measurements demonstrated a strong correlation between calculated and measured velocities (r > 0.98) and good reproducibility for both diameter and velocity measures.
Impact:
- This validated system provides a reliable, non-invasive tool for assessing peripheral artery hemodynamics.
- It can aid in the diagnosis and monitoring of vascular conditions affecting the carotid, femoral, and humeral arteries.
- The study establishes high accuracy and reproducibility, supporting its clinical utility.
Abstract:
The purpose of this study is the validation of a 2D-echography and range-gated system to measure internal diameter, and instantaneous blood flow velocity, and to calculate the blood flow, in peripheral arteries (i.e. common carotid artery, femoral artery, and humeral artery). The artery is first visualized using the echographic array probe, its internal diameter (D) is determined and its cross sectional area (S) calculated; the array of the ultrasonic system and the doppler probe are attached and forme a fixed angle. The range-gated doppler system allows the measurement of instantaneous blood flow velocity, with a position of the sample volume covering the internal diameter. Instantaneous velocities are integrated on several cardiac cycles to calculate the mean velocity (Vm). (S. Vm) measures the blood flow. The echographic array probe allows a control of the doppler beam position. In vitro velocities have been measured (N = 20). The fixed angle is 38 degrees 30'; there is an obvious relationship between the calculated and the measured velocities (r = 0.982; p less than 0.0001). The intra-observer reproducibility of measures on common carotid arteries (CCA), femoral arteries (FA), and humeral arteries (HA). In 7 normal patients is, respectively: diameters: (4.9%, 4.12%, 10.2%); velocities: (8.9%, 10.6%, 10.2%). The inter-observers reproducibility is respectively: diameters: (5.6%, 5.4%, 11.4%); velocities: (6.5%, 5.7%, 6.3%). The comparison of 11 measures of diameters and velocities with 20 range-gated doppler gives an obvious relationship (respectively, r = 0.99 p less than 0.0001, r = 0.996, p less than 0.0001).(ABSTRACT TRUNCATED AT 250 WORDS)