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Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis
Published on: March 7, 2018
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A simple and sensitive method for visual detection of heparin using positively-charged gold nanoparticles as
1Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Materials Science, Shaanxi Normal University, Xi'an 710062, PR China.
Abstract:
The electrostatic interaction between the negatively-charged heparin and the positively-charged gold nanoparticles leads to aggregation of gold nanoparticles and a color change from red to blue in solution, thus providing a simple and visual approach to colorimetric detection of heparin.

