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An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
How to diagnose giant cell arteritis
R J Meisner1, N Labropoulos, A P Gasparis
1Division of Vascular Surgery, Department of Surgery, Stony Brook University Hospital, NY 11794-8191, USA. robert.meisner@stonybrook.edu
Aim:
Current debate on how to diagnose giant cell arteritis (GCA) has strayed from the traditional approach of temporal artery biopsy and has instead explored the effectiveness of alternative imaging modalities.
Methods:
We have reviewed the literature and pooled published results for temporal artery imaging including magnetic resonance imaging (MRI), Duplex ultrasound, positron emission tomography-computed tomography (PET-CT) scan.
Results:
The results of this review show that ultrasound and MRI both represent viable options for evaluation of GCA; however utilizing ultrasound first may be the best first option in diagnostic tools. In 1990 the American College of Rheumatology offered criteria for positive pathology in GCA.
Conclusion:
In this study, we propose a risk stratification criteria as well as an algorithm for the best diagnostic approach when GCA is suspected.
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