Antiquated tests within the clinical pathology laboratory

Area of Science:

• Clinical Laboratory Medicine
• Diagnostic Testing Evaluation

Background:

• Many traditional laboratory tests may no longer offer significant clinical utility.
• The evolving landscape of medical diagnostics necessitates a review of established testing protocols.

Purpose of the Study:

• To present evidence supporting the discontinuation of laboratory tests lacking current clinical utility.
• To identify specific tests that are considered antiquated in modern clinical practice.

Main Methods:

• A review of published literature was conducted to assess the performance and clinical utility of 10 selected tests.
• Data from the College of American Pathologists' Proficiency Testing Program (1993-2008) were analyzed.
• Alternative testing methods were suggested where applicable.

Main Results:

• A clear national trend indicates a reduction or elimination of the 10 evaluated laboratory tests.
• The selected tests, including creatine kinase-MB, myoglobin, and erythrocyte sedimentation rate, demonstrate limited current clinical value.

Conclusions:

• Clinical laboratorians and their colleagues should critically evaluate their test menus.
• Discontinuation of tests without proven clinical benefit is recommended, as effective alternatives are often available.