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Updated: Jun 5, 2026
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
[Surgical treatment of maxillary tumors]
Gilad Horowitz1, Ziv Gil, Oren Kavel
1Department of Otolaryngology Head and Neck Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv University, Jerusalem, Israel.
Objectives:
Tumors originating in the maxillary sinus are relativeLy rare. The aim of this article is to review the indications, diagnosis and treatment of patients with maxillary tumors operated at Tel Aviv Sourasky Medical Center during the period 1999 - 2008.
Methods:
A total of 174 patients underwent surgery due to neoplasms originating in the maxillary sinus: 118 patients (68%) had malignant and 54 (32%) had benign tumors.
Results:
The most common malignancy was squamous cell carcinoma (40%), and the most common benign tumor was juvenile nasopharyngeal angiofibroma (36%). A total of 146 patients (84%) underwent partial maxillectomy and 28 (16%) total maxillectomy. In 9 cases, resection was extended to include the eye socket or base of skull, due to tumor invasion. Thirty-five patients had post-operative complications, with local wound infection being the most common complication (n = 12). Among patients with malignant tumors, 75 are alive without disease (67%), 12 (10%) are alive with disease and 31 (23%) died of disease or other causes.
Conclusions:
The surgical approach to malignancies of the maxilla is safe and effective. A multidisciplinary team approach is essential to deliver appropriate therapeutic means for these patients.
