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Updated: Jun 5, 2026

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
Published on: September 16, 2011
[Several indexes needed for evaluation of hypersensitive reactions of the medicine]
Abstract:
Drug allergy represents the dominant problem of twenty first century. Number of heavy allergic reactions is increased that is obvious through the increasing number of hospitalizations. Mentioned problem is extended through the rapid development of pharmaceutical industry. Lots of drugs industrialized on a drug market aren't analyzed properly and give rise to undesirable allergic reactions. Diagnostics of drug allergy requests some methodical approaches: detailed collection of Allergic anamnesis and appropriate in vivo and in vitro test sampling. Questionnaire, formulated under the patronage of European Association of Allergologist and clinical Immunologists ensures standard directives for the collection of detailed allergic Anamnesis. Foreseeing the regional peculiarities, we have formulated the simplified version of the questionnaire. In case of positive answer analysis are accompanied and made by Allergologist who makes the sampling of in vivo and in vitro tests.
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