Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Depressive Disorders: Etiology

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

Depressive Disorders: MDD and Dysthymia

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...

Depression: Overview

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...

Community Based Intervention

Community Based Intervention

Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mechanisms of mindfulness-based cognitive therapy in difficult-to-treat depression: moderation and mediation analyses from the RESPOND trial.

Psychological medicine·2026

Same author

Impact of Menopause and Clinical Considerations in Patients With Inflammatory Bowel Disease.

Gastroenterology & hepatology·2026

Same author

Esophageal Stricture in a 5-Year-Old Child with Epidermolysis Bullosa: Case Report of a Rare Complication at a Very Young Age.

Case reports in gastroenterology·2026

Same author

Efficacy and Moderators of Mindfulness-Based Cognitive Therapy in Difficult-to-Treat Depression: A Systematic Review and Individual Participant Data Meta-Analysis.

Psychotherapy and psychosomatics·2026

Same author

Celiac disease presenting As recurrent encephalopathy and seizures.

Oxford medical case reports·2026

Same author

Exploring how to improve experimenter training in experimental psychopathology: Lessons from and for the trauma film paradigm.

Clinical psychology review·2026

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

Suicidal imagery in a previously depressed community sample.

Catherine Crane¹, Dhruvi Shah, Thorsten Barnhofer

¹Department of Psychiatry, University of Oxford, UK. catherine.crane@psych.ox.ac.uk

Clinical Psychology & Psychotherapy

|January 22, 2011

Summary

Suicidal patients often experience vivid suicide imagery during depressive episodes. This imagery may differ in meaning and distress levels, suggesting potential therapeutic targets for depression and suicide prevention.

More Related Videos

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Related Experiment Videos

Last Updated: Jun 5, 2026

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Area of Science:

Psychology
Psychiatry
Clinical Psychology

Background:

Suicide-related imagery is a known phenomenon in individuals with a history of suicidal ideation or behavior.
Previous research indicates vivid imagery during depressive episodes.

Purpose of the Study:

To replicate findings on suicide-related imagery in a community sample of adults with a history of depression.
To explore the nature and meaning of suicide imagery in relation to suicidal ideation and behavior.

Main Methods:

A community sample of 27 adults with a history of depression was interviewed.
Participants were assessed for suicidal ideation, behavior, and suicide-related imagery.

Main Results:

The majority of participants with prior suicidal ideation/behavior reported vivid suicide imagery during depressive episodes.
Some participants without reported suicidal ideation also described death/suicide imagery, sometimes with protective meanings.
Higher suicidality severity correlated with lower distress and higher comfort related to imagery.

Conclusions:

Suicide-related imagery is a significant aspect of depression and despair.
The meaning attributed to imagery may differ between those with and without a history of suicidal acts.
Targeting suicide imagery directly could be a valuable therapeutic approach for suicidal patients.