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Updated: Jun 5, 2026

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats
Published on: April 7, 2023
[Effect of benzimidazole derivative with hypoglycemic activity on reproduction processes in females rats]
Abstract:
Toxicological experiments showed that the new benzimidazole derivative with hypoglycemic action--diabenol--influences the sexual activity and processes of female fertilization. The estrous cycle, sexual activity and quality of fertilization were activated at females upon the administration of diabenol in a therapeutic dose of 5 mg/kg. It is established that the drug administration in a toxic dose of 160 mg/kg suppresses the sexual activity and, at the same time, does not affect the estrous cycle and quality of fertilization in females.
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