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Updated: Jun 5, 2026

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer
Published on: July 6, 2017
[Squamous cell carcinoma of the colon. A rare histological entity]
P Ambe1, S Shadouh, S Granetzny
1Chirurgische Klinik, St. Elisabeth Kreiskrankenhaus Grevenbroich, Akademisches Lehrkrankenhaus der RTWH Aachen, Von-Werth-Strasse 5, Grevenbroich, Germany. peter.ambe@kkh-ne.de
Abstract:
Squamous cell carcinoma of the colon is an extremely rare histopathological entity accounting for less than 0.025% of all colonic malignancies. Mucosal metaplasia is believed to be the leading cause of this form of carcinoma and the presentation and diagnosis is the same as for adenocarcinoma. Surgery is the treatment method of choice and adjuvant radiation and chemotherapy are recommended in advanced stages of the disease. Advanced squamous cell carcinoma seems to have a poorer prognosis compared to advanced adenocarcinoma.
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