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Updated: Jun 5, 2026

Screening Foodstuffs for Class 1 Integrons and Gene Cassettes

Screening Foodstuffs for Class 1 Integrons and Gene Cassettes

Published on: June 19, 2015

Class 1 integron in staphylococci.

Zhenbo Xu¹, Lin Li, Lei Shi

¹College of Light Industry and Food Sciences, South China University of Technology, Guangzhou, China.

Molecular Biology Reports

|January 25, 2011

Summary

Class 1 integrons are emerging as key drivers of antibiotic resistance in methicillin-resistant staphylococci (MRS). This review details their prevalence and role in conferring resistance in these critical Gram-positive pathogens.

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Screening Foodstuffs for Class 1 Integrons and Gene Cassettes

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Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Multiplex PCR Assay for Typing of Staphylococcal Cassette Chromosome Mec Types I to V in Methicillin-resistant Staphylococcus aureus

Published on: September 5, 2013

Area of Science:

Microbiology
Molecular Biology
Public Health

Background:

Methicillin-resistant staphylococci (MRS) are a significant public health concern, causing prevalent nosocomial infections globally.
MRS are recognized as

Purpose of the Study:

To review the prevalence and characteristics of class 1 integrons in clinical MRS isolates.
To analyze the association between class 1 integrons and antibiotic resistance in MRS.
To investigate the role and evolution of integrons as determinants of antimicrobial resistance in Gram-positive bacteria.

Main Methods:

Systematic investigation of integrons in hundreds of staphylococci strains between 2001 and 2006.
Review of existing literature on class 1 integrons in Gram-negative and Gram-positive bacteria.
Analysis of prevalence, occurrence, and correlation with antibiotic resistance.

Main Results:

Class 1 integrons are identified as a novel antibiotic resistance mechanism, primarily studied in Gram-negative organisms.
Limited knowledge exists regarding integrons in clinical Gram-positive bacteria like MRS.
This review focuses on the development, prevalence, and role of class 1 integrons in MRS.

Conclusions:

Class 1 integrons play a significant role in the antibiotic resistance of MRS.
Further research into integrons in Gram-positive bacteria is crucial for understanding and combating antimicrobial resistance.
Surveillance of integrons in clinical MRS strains is of utmost importance for public health.