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Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

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Related Experiment Video

Updated: Jun 5, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

Perinatal tuberculosis: two unusual cases.

S Basu1, A Kumar, B K Das

  • 1Department of Paediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. drsriparnabasu@rediffmail.com

Annals of Tropical Paediatrics
|January 26, 2011
PubMed
Summary
This summary is machine-generated.

Two immunocompromised infants with perinatal tuberculosis experienced severe lung disease. Diagnosis was confirmed using PCR, highlighting the importance of early detection in vulnerable newborns.

Related Experiment Videos

Last Updated: Jun 5, 2026

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
03:47

A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients

Published on: October 25, 2024

Area of Science:

  • Pediatric Infectious Diseases
  • Neonatal Immunology
  • Mycobacterial Infections

Background:

  • Perinatal tuberculosis is a rare but serious condition in newborns.
  • Immunocompromised infants are at increased risk for severe disseminated disease.
  • Maternal tuberculosis and HIV co-infection pose significant challenges for infant health.

Observation:

  • Two cases of immunocompromised infants with perinatal tuberculosis are presented.
  • Both infants exhibited bilateral miliary mottling on lung imaging.
  • Risk factors included maternal tuberculosis and infant prednisolone use or perinatal HIV infection.

Findings:

  • Polymerase Chain Reaction (PCR) confirmed tuberculosis in both infants.
  • Diagnosis was achieved through PCR analysis of serum and cerebrospinal fluid (CSF).
  • Maternal infections included tuberculous endometritis and pulmonary tuberculosis, alongside HIV infection in one family.

Implications:

  • Highlights the diagnostic utility of PCR in early identification of neonatal tuberculosis.
  • Emphasizes the need for heightened awareness and screening for tuberculosis in immunocompromised infants and their families.
  • Underscores the challenges in managing tuberculosis co-infected with HIV in the perinatal period.