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Decellularization-Based Quantification of Skeletal Muscle Fatty Infiltration
Published on: June 9, 2023
Impact of obesity on total and cardiovascular mortality--fat or fiction?
Beatriz Cepeda-Valery1, Gregg S Pressman, Vincent M Figueredo
1Department of Internal Medicine, Albert Einstein Medical Center, 5401 Old York Road, Klein Professional Building, Suite 300, Philadelphia, PA 19141, USA.
Abstract:
Obesity is an excessive accumulation of fat that can impair health. Because the direct measurement of body fat is difficult to perform, a number of anthropometric measures have been employed as surrogates, of which BMI is the most commonly used. However, its usefulness has been questioned as a BMI in the overweight and mildly obese range is associated with improved survival and fewer cardiovascular events than a BMI in the normal range, a phenomenon known as the 'obesity paradox'. Waist circumference, waist-to-hip ratio, and waist-to-height ratio take into consideration body-fat distribution, especially abdominal obesity, and seem to predict cardiovascular risk better than does BMI.
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