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Related Experiment Video

Updated: Jun 5, 2026

Optical Trapping of Plasmonic Nanoparticles for In Situ Surface-Enhanced Raman Spectroscopy Characterizations
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Shot-noise limited detection for surface plasmon sensing.

Xi Wang1, Michael Jefferson, Philip C D Hobbs

  • 1Department of Electrical and Computer Engineering, University of California, Davis, Davis, CA 95616, USA.

Optics Express
|January 26, 2011
PubMed
Summary

Surface plasmon sensing achieves unprecedented resolution for refractive index changes. This advancement utilizes electronic noise cancellation for highly sensitive interface measurements.

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Area of Science:

  • * Physics
  • * Analytical Chemistry
  • * Materials Science

Background:

  • * Surface plasmon resonance (SPR) is a label-free technique for detecting molecular interactions.
  • * Conventional SPR systems are limited by laser intensity noise, hindering ultra-sensitive measurements.
  • * Achieving shot-noise-limited performance is crucial for advancing SPR applications.

Purpose of the Study:

  • * To demonstrate surface plasmon sensing in the shot-noise-limited regime.
  • * To achieve ultra-high resolution for refractive index changes at interfaces.
  • * To investigate the impact of active noise cancellation on SPR sensitivity.

Main Methods:

  • * Employed active electronic noise cancelling to suppress laser intensity fluctuations.
  • * Optimized the sensing wavelength to maximize sensitivity to refractive index variations.

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Last Updated: Jun 5, 2026

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  • * Operated the SPR system at low input power (1 mW) to achieve shot-noise-limited performance.

    • Main Results:

    • * Demonstrated SPR sensing in the shot-noise-limited regime.
    • * Achieved a refractive index resolution of 10-10/√Hz.
    • * Successfully measured refractive index changes in air due to pressure variations, validating the system's performance.

    Conclusions:

    • * Active noise cancellation enables SPR to operate in the shot-noise-limited regime.
    • * This approach significantly enhances resolution for detecting interfacial refractive index changes.
    • * The developed method offers a powerful tool for high-sensitivity sensing applications.